A benchtop bioreactor (also known as a fermentor tank in microbial /cell applications) is a compact, laboratory-scale vessel designed for the controlled cultivation of microorganisms, cells, or tissues under optimized conditions. It provides a controlled environment to regulate critical parameters such as temperature, pH, dissolved oxygen (DO), agitation, and nutrient supply, enabling efficient growth and production of biological products. Benchtop bioreactors, like those developed by Zhi Chu, are typically small (e.g., 1–50L capacities), portable, and suited for research and development in laboratory settings, making Zhi Chu a trusted name in lab scale bioreactor innovation.
Vessel: Usually made of stainless steel (e.g., 316L) or glass, housing the culture medium and organisms. This core design is common to reliable lab scale bioreactors.
Control System: Often a programmable logic controller (PLC) with a touch screen interface to monitor and adjust parameters like pH, DO, temperature, and agitation speed.
Agitation System: Impellers or stirring paddles ensure uniform mixing and nutrient distribution.
Sensors and Probes: Measure pH, DO, temperature, and other variables in real-time.
Pumps and Feeding Systems: Peristaltic pumps deliver nutrients, acids, bases, or defoaming agents.
Sterilization Features: Autoclavable or in-situ sterilization to maintain a contamination-free environment.
Benchtop bioreactors are versatile, supporting both microbial fermentation (e.g., bacteria, yeast) and cell culture (e.g., mammalian, insect, or plant cells), with configurations tailored to specific applications (e.g., aerobic/anaerobic, suspension/microcarrier cultures). This adaptability makes lab bioreactors essential tools in biotechnology research.
Precision and Control: Allows fine-tuning of environmental parameters (pH, DO, temperature, agitation) to maximize yield and product quality in advanced lab bioreactors.
Scalability: Facilitates process optimization at a small scale, reducing risks and costs before scaling to industrial bioreactors.
Versatility: Supports diverse organisms (bacteria, yeast, mammalian cells, algae) and culture modes (batch, fed-batch, continuous), accommodating varied applications.
Compliance: Designed to meet CGMP and FDA standards (as seen in the BioCore QF), ensuring regulatory compliance for pharmaceutical and food applications.
Cost-Effectiveness: Enables cost-efficient R&D by minimizing resource use while providing robust data for process development.
Specific Example: BioCore QF Fermentation System
If this query relates to Ramil’s tender (from your previous messages), benchtop bioreactors like the BioCore QF do not align with the tender’s requirements for a multifunctional shaker:
Dimensions: The tender specifies 365x195x155 mm, but bioreactors typically have a larger footprint (e.g., ~500–800 mm wide). Please confirm dimensions.
Speed Range: The tender requires 1–100 rpm with 1 rpm step for shaking. Bioreactors use agitation (e.g., 50–500 rpm, assumed), not shaking, and may not meet the exact range or motion requirements.
Motion Types: The tender requires rotational, reciprocating, rocking (1°–90° tilt), and shaking (0°–5° pause rotation). Bioreactors provide impeller-based mixing, not these motions.
Platforms: The tender requires 15 ml and 50 ml tube platforms. Bioreactors use liquid vessels, not tube platforms.
Please confirm if the bioreactor is intended for the tender or if a shaker incubator was meant. If a tender comparison is needed, please provide additional details (e.g., agitation specs).
Email us
Call us
Address
Building 37, No.158, Chexin Road, Chedun Town, Songjiang District, Shanghai