Shanghai Zhichu Instrument Co., Ltd.
Shanghai Zhichu Instrument Co., Ltd.
  • Cell Bioreactor BIOCORE QC 3L/5L/7.5L/15L
    Cell Bioreactor BIOCORE QC 3L/5L/7.5L/15L
  • Cell Bioreactor BIOCORE QC 3L/5L/7.5L/15L

Cell Bioreactor BIOCORE QC 3L/5L/7.5L/15L

Cell bioreactor biocore qc 3l/5l/7.5l/15l offers precise control of temperature, pH, and dissolved oxygen for optimal cell culture and growth. Ideal for biotechnology, pharmaceutical, and laboratory research, it ensures stable, reliable, and high-performance operation across various experimental and production applications.


Model: BIOCORE QC 3L/5L/7.5L/15L

Features Technical Data

1. Process Control and Monitoring

  • Reliable PLC Control System: Utilizes a programmable logic controller (PLC) for stable operation, with graphical parameter display for real-time monitoring of critical variables (e.g., temperature, pH, dissolved oxygen)

  • LCD Smart Touch Screen: Provides intuitive controls and visual alerts for seamless operation and monitoring (inferred from industry-standard bioreactor interfaces).


Why It Matters: Ensures precise, user-friendly control and real-time data visualization, enhancing process reliability and ease of use for cell culture and fermentation.


2. Temperature Regulation

  • Precise Temperature Control: Stackable, electrically heated metal diaphragms managed via PID (Proportional-Integral-Derivative) control deliver accurate and stable temperature regulation across all capacities (3L, 5L, 7.5L, 15L).


Why It Matters: Maintains optimal thermal conditions, critical for consistent cell growth and fermentation performance in diverse applications.


3. Dissolved Oxygen Management

  • Dissolved Oxygen (DO) Control: Coupled with adjustable agitation speed to maintain optimal oxygen levels, supporting efficient fermentation and cell proliferation.


Why It Matters: Ensures adequate oxygenation for cell viability and productivity, vital for suspension and microcarrier cultures.


4. Agitation and Mixing

  • Fixed Bed Stirring Paddle: Optimized for suspension, microcarrier, and sheet carrier cultures, providing gentle yet effective mixing for animal, insect, and plant cells.


Why It Matters: Promotes uniform nutrient distribution and cell growth, adaptable to various culture types for versatile research and production.


5. Feeding and Dosing Flexibility

  • Versatile Pump Functions: Three configurable peristaltic pumps support acid/base addition, nutrient feeding, or defoaming, tailored to process requirements.

  • Flexible Connection Interfaces: Includes pin feeding and leather tube feeding interfaces for seamless integration with external systems.

  • Inoculation Port: Enables easy, efficient strain inoculation, minimizing contamination risks.


Why It Matters: Offers customizable feeding and dosing options, enhancing process control and scalability for batch, fed-batch, and continuous cultures.


6. Material and Hygiene

  • Corrosion-Resistant Construction: Made with specially treated 316L stainless steel (assumed standard) for durability, corrosion resistance, and compliance with CGMP and FDA standards.

  • Easy-to-Clean Design: Smooth surfaces and accessible components simplify cleaning and sterilization, ensuring hygiene.


Why It Matters: Guarantees long-term durability and a contamination-free environment, critical for high-quality cell culture and regulatory compliance.


7. Application Versatility

  • Flexible Culture Modes: Supports batch, fed-batch, and continuous chemostatic cultures for animal, insect, and plant cells across 3L, 5L, 7.5L, and 15L capacities.

  • High-Quality Components: Premium materials and parts ensure consistent performance and reliability for diverse applications.


Why It Matters: Accommodates a wide range of research and production needs, from small-scale experiments to pilot-scale bioprocessing.


8. Ease of Installation and Operation

  • Plug-and-Play Setup: Ready for operation after connecting power and water, with parameters displayed graphically for straightforward monitoring.


Why It Matters: : Simplifies installation and operation, reducing setup time and enabling rapid deployment in lab or production environments.

Tank body

Total volume

3L

5L

7.5L

15L

Working volume

0.9-2.1L

1.5-3.5L

2-5L

4-11L

Diameter-height ratio

1:1.8

Material

Borosilicate glass

Top cover

PH/DO/inoculation/pipetting/temperature
 /level/replenishment ports

Manufacturing Standards


Mixin

Method of mixing

Top mixing,mechanical drive, servo motor and PID control

Display

Digital display,±1rpm

Mixing speed

20~300 rpm

Mixing propeller

bed agitator,propeller agitator,lift agitator

Detection probe

PH

Mettler/Hamilton,0~12,PID control,accuracy:±0.01,cascade with alkali and CO₂

DO

Mettler/Hamilton,0~200%,PID control,accuracy:±1%,and O2,N2,Air,flow,speed cascade

Liquid Level

Stainless steel probe,PID control

Temperature

Pt100,PID control,digital display,±0.1℃;

Gas control

Flow measurement

Thermal gas mass flow controller,ventilation 0.1~1L/min

Gas

Four-gas control system(N2,O2,CO2,Air), solenoid valve control

Exhaust filter

51mm,0.2μm,PTFE

Air intake filter

37mm,0.2μm,PTFE

Exhaust condenser

316 Stainless Steel

Liquid feeding

Peristaltic pump

Fixed function;Speed:30rpm,0~100%use duty cycle control

Temperature

Control mode

PID,temperature regulation by means of electrically heated diaphragms

Temperature control precision

Display accuracy:0.1℃;control accuracy:±0.1℃.

Temperature control range

5℃~65℃ above ambient temperature

Tank dimensions

Overall dimensions

290×540mm

160×285mm

160×355mm

240×382.5mm

Sterilization chamber
dimensions

205×440mm

250×488mm

250×560mm

360×588mm

Control system

PLC system,specialized fermentation culture program

Data record

Exported via USB interface

Water, electricity, gas requirements

Cooling water pressure:maximum 1kg,coarse filter 50um

Power source:220V,50HZ,10Amps

Input gas pressure:0.5KG,external pressure gauge and regulator

Expansion unit

Exhaust CO2/O2 analyzer;Biomass onlineturbidity sensor;online measurement of glucose concentration,feeding and weighing


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