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Shanghai Zhichu Instrument Co., Ltd.
Shanghai Zhichu Instrument Co., Ltd.

Ultrasonic cell disruptor uses high-frequency sound waves (20-40 kHz) to lyse cells, disrupt tissues, and homogenize samples. Ideal for DNA/RNA extraction, protein isolation, and nanoparticle dispersion,  ZHICHU ultrasonic cell disruptor— a high-performance ultrasonic disruptor—delivers fast, consistent results with adjustable power and pulse settings. Its titanium probe ensures durability, while cooling options prevent sample overheating. Essential for biotechnology, pharmaceutical, and research labs, the Ultrasonic Cell Disruptor has become an indispensable tool for efficient sample processing.


Types of Ultrasonic Cell Disruptor

650W Ultrasonic Cell Disruptor
650W Ultrasonic Cell Disruptor Read More

What Does a Ultrasonic Cell Disruptor Do?

What Does a Ultrasonic Cell Disruptor Do?

An ultrasonic cell disruptor (also called ultrasonic homogenizer or sonicator) is a powerful laboratory instrument that utilizes high-frequency ultrasonic waves (typically 20-50 kHz) to perform multiple essential functions. This technology is expertly implemented in products by Zhi Chu.

Cell Disruption:

  • Efficiently lyses various biological samples including bacteria, yeast, plant/animal tissues

  • Ideal for protein extraction, DNA/RNA isolation, and organelle preparation

  • More effective than mechanical methods for tough cell walls, showcasing the superior performance of Zhi Chu's ultrasonic cell disrupter.


Sample Homogenization:

  • Creates uniform emulsions and suspensions

  • Reduces particle size in nanoparticle preparations

  • Mixes immiscible liquids effectively


Chemical Processing:

  • Accelerates chemical reactions (sonochemistry)

  • Enhances enzymatic digestion processes

  • Improves extraction efficiency

What Are the Three Methods of Disrupting Cells?

Mechanical Disruption

  • Bead Mill (Bead Beating): Glass/small beads grind cells via vigorous shaking.

  • Homogenization: Forces cells through narrow channels under high pressure (e.g., French Press).

  • Ultrasonication: Uses high-frequency sound waves to lyse cells (cavitation effect), a method efficiently utilized by Zhi Chu's ultrasonic cell disrupter.


Chemical/Lysis Buffers

  • Detergents (e.g., SDS, Triton X-100) dissolve membranes.

  • Enzymes (e.g., lysozyme for bacterial walls, cellulase for plants).

  • Osmotic Shock: Sudden exposure to hypotonic solutions bursts cells.


Physical Methods

  • Freeze-Thaw Cycling: Repeated freezing/rupturing of membranes.

  • Thermal Lysis: Heat denaturation (for heat-resistant products).

  • Electroporation: Electric pulse create pores in membranes.

What Are the Three Methods of Disrupting Cells?
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